I used Anoro for a short while but insurance would not pay (too expensive) so I now use Incruse Elippta neither made me uncomfortable. Maybe you are not blowing out air before sucking in medicine. I was also told by a respiratory nurse to not wrap your lips around device but to blow out good amount of air and just use device with an open mouth. This way it is not hitting the back of your throat which is probably what is happening. Hopeful this is helpful.

This is from the Anoro website:

ANORO can cause serious side effects, including:
sudden breathing problems immediately after inhaling your medicine. If you experience this, stop using ANORO and call your healthcare provider right away.
serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms:
rash
hives
swelling of your face, mouth, and tongue
breathing problems
effects on heart
increased blood pressure
a fast or irregular heartbeat, awareness of heartbeat
chest pain
effects on nervous system
tremor
nervousness
new or worsened eye problems, including acute narrow-angle glaucoma that can cause permanent loss of vision if not treated. Symptoms may include:
eye pain or discomfort
nausea or vomiting
blurred vision
seeing halos or bright colors around lights
red eyes

If you have these symptoms, call your healthcare provider right away before taking another dose.
urinary retention. People who take ANORO may develop new or worse urinary retention. Symptoms may include:
difficulty urinating
painful urination
urinating frequently
urination in a weak stream or drips

https://www.symbicorttouchpoints.com/?source=sy... You can get it ffree