I found this on the net: https://copd.net/treatment/medication-overview/...spiriva-respimat-spiriva-handihaler/ (for further information)

What is the difference between Spiriva HandiHaler and Spiriva Respimat?

Spiriva Respimat and Spiriva HandiHaler both have the same active ingredient in the medicine: tiotropium bromide. However, the medicine is delivered in different ways, and there are some differences in the side effects that they cause.

The medicine in Spiriva HandiHaler comes in a dry powder contained in a capsule that is put into a special inhaler. The patient takes the medicine by breathing in two inhalations through the HandiHaler. The medicine lasts for 24 hours, so patients take one dose (two inhalations) of Spiriva HandiHaler per day in the morning. Patients use a new capsule for each dose.

Spiriva Respimat uses a different kind of special inhaler. It delivers a very slow-moving mist that is designed to help the patient inhale the medicine easier. The amount of medicine the patient takes in does not depend on how fast they are able to inhale. Patients receive one dose per day, which lasts for 24 hours.
How effective are Spiriva HandiHaler and Spiriva Respimat?

The effectiveness of Spiriva HandiHaler has been tested in several large studies. The results showed that it had positive effects on both lung function and the number of COPD flare-ups. Patients treated with Spiriva HandiHaler for 4 years:

Had significantly better overall lung function, measured by spirometry
Had a reduced risk of flare-ups
Had a longer time (4-5 months) before the first flare-up
Had to use their rescue inhalers less often

The studies that tested Spiriva Respimat had similar results. Overall, it improved patients’ lung function and reduced their likelihood of having COPD flare-ups.

@A MyCOPDTeam Member I was also on the caplet dispenser for around 2 years and on bad days i dint have the energy or the breath to be able to inhale it up the Doc changed me over to Spiriva Respimat on my last stay in Hospital and I find it so much easier to inhale I have not found any negatives against it in the 6 months I have been using it

Mentioned Users

A MyCOPDT...

Also, I have just been recommended a non-U.S. website for reduced prices in all medicines. I found this on the American Lung Association website called "Team Inspire." The name of the company is All Day Chemist and I have found them to be very thorough, responsive to questions and all in all a great company. They deal in generics, so you need to know the chemicals in your current medications, which you can find on the labels.....hope this helps, Lori!

The only difference I found is that my health plan covers the powder and not the mist, therefore I can't comment on the mist.

the spray is a mist so it gets keep into the lungs, the powder gets hung up before it goes in far enough. Spray is much better.