Seascape, I don't like to take albuterol nebulizer stuff because a few years ago I took too much one night and it put my heart into afib. I ended up needing two heart operations (ablation both sides). But the good part is my heart is fixed, and I don't even need blood thinners anymore. I just don't want to put myself back into that situation again. I guess if I had to I would use ProAir rescue inhaler that I have available, but I have not needed it since the operations. I am allergic to statin drugs, but I don't need them right now as my LDL cholesterol seems to be under control. In about 2005 a statin drug ruined every muscle in my body in 28 days. I was told it was because the statin stopped my body from making it's own CoQ10 which our muscles need. My anti-statin doctor is retiring Jan 1st. I heard some of his anti-statin trials failed for lack of funding. You don't think the pharmaceutical industry had anything to do with that, do you? Our heart and lungs work together, so we need to be sure we keep both of them operating smoothly.

You're asking some good questions to which we obviously have no answers yet. Personally I suspect that you may belong to a rather small phenotype we haven't identified yet, but that's just my opinion and I'm not a scientist or researcher. I do know that there are researchers who are trying to identify various phenotypes in hopes of using that information to help develop more personalized medicine. Right now our approach to COPD is pretty much a one size fits all, and if you have odd symptoms, like the person who asked Rolland to post the question, you have a hard time even finding other people who have similar symptoms. If you want to know what research is being done, you can get some information from the ALA, the COPD Foundation and the NIH. Information on clinical trials can be found on www.clinicaltrials.gov. That will give you some idea of what's going on, but there's a lot more that is being done by private research institutes and academic settings. Unfortunately I don't think think there's any data base that keeps track of all of it. Controlling excess mucus production is being researched, but there's nothing definitive that I'm aware of at this point.

I really don't think it is diet, but I do think there is some connection with the lung-gut axis like was described in the website RollandO sent me
( https://www.nature.com/articles/s(Phone number can only be seen by the question and answer creators) ).
I really don't think it is necessarily disease related (because I have not shown any color in my sputum since I was run through a course of antibiotics many months ago and have not been sick in a long time). But something is being sent to the lungs when the gut bio system starts to work on what was put in the stomach (any type of food or liquid). It makes sense to me. Scripps Research recently published a video on what happens to send signals from the gut to the brain, so maybe it is also sending a signal from the gut to the lungs. Salk Institute is working on a modified Fisetin Trial of CMS121 that is affecting the brain, and it seems to help my lungs. Mayo Clinic has been testing Fisetin for COVID19. Maybe something like that with a smaller dosage for continuous usage would work for COPD???????? There are other things like flavonoids that have shown some good effects. What else can we find and what dosage should be used? How do we get someone to seriously look into this? (During my life time)

I personally know at least 6 people in my small social circle of friends that have the same symptoms, so it must be a much larger number of suffers than you suggest.

Merry Christmas to all of you