Yes indeed ❤️

It's important to be aware of the potential side effects, but here's something you may not know. When they do clinical trials for any med, they have to keep track of any "adverse" events that occur, beginning with death from any cause and going down to stubbed toes if that's considered an "adverse event". If the med is approved and actually goes to market, the FDA requires them to list all the potential side effects that were noted as adverse events. Some times there's a side effects list and then an additional list which gives you some idea of which ones are most common. The thing is that they never tell you how many people actually experienced those side effects during the trial and no one ever is required to prove that this med caused this reaction. They just have to list them; all of them.

Glad you're doing well on Advair. I'm definitely of the "if it ain't broke, don't fix it" school......but sometimes I can change my mind; that's a woman's prerogative!

Jean, I am very grateful for your sound advice on here and always given in a caring manner, you are awesome!! Right now advair works really well for me, I can even go w/o oxygen for a time period, I don’t get to see a pulmonologist until August, my pcp prescribed it, did prescribe trelegy first But I was a scaredy-cat and was afraid of the side effects I read about, but right now I’m doing great on advair

It's important to have a pulmonologist who is familiar with all of these so if one doesn't work well for you, another might. For years I took Advair, but had no luck at all with LAMAs. I tried the first two when they were launched, and they actually made my breathing worse. Along came Trelegy and my pulmonologist said lets' try. I reminded him that I have never done well with a LAMA, and that's one of the three ingredients. He really pushed me and since I still had Advair in my supply, I finally agreed. It has made a big positive difference and that Advair is now out of date..

Here's the real point: you can't go by what anyone tells you about how inhalers work for them. Everyone's different and everyone can respond to different inhalers differently. Don't EVER make a decision about what inhaler to use based on other people's responses, because yours could very easily be totally different. And don't ever wait to say this isn't working to your doc.....they need to know because there are lots of choices!

I hope this helps..........

In order to understand Advair and Trelegy, it's important to know the classifications of the inhalers most commonly prescribed for COPD. There are three: long acting muscarinic agents LAMA), long acting beta agonists (LABA) and inhaled corticosteroids (ICS). There are also short acting versions of all of these, but they're not often prescribed unless you don't respond well to the long acting version. The difference is in how many times a day you have to use your inhalers. If you google the COPD Foundation's pocket guide for patients, you will find which inhalers are in each of the categories.

These three classes of meds form the backbone of COPD treatments. When people are diagnosed, they often start with either a LAMA or a LABA/ICS combination. If that's not enough, the other is added. That's often talked about as "triple therapy" and if you're told that's there's nothing more they can do for you, they mean that you're already getting the three classes of meds available. You can always try different ones in the class. One thing to remember is that even though the meds are in the same class, each manufacturer has individual molecules they can use for their particular LAMA, for instance. Not everyone responds really well to those individual molecules, which is why you see stories from patients saying such and such inhaler didn't do a thing for me. Very often determining which inhalers will work best for you is an exercise in frustration, because you may have to try several before you find one that works well.

These are often combined to reduce the number of inhalers you have to use, and there's some clinical evidence that in combination they do a better job than if taken separately. In either short or long versions, these are all maintenance medications. They will make a difference over time, but it will take a while for them to take effect, and often people don't know how much they made a difference until they stop taking them.

Advair is a combination LABA and ICS. It was one of the first combined inhalers available; I started taking it in 2005, I think. It was very successful, as is Symbicort; also a LABA/ICS combination.

Trelegy is a combination LABA/LAMA/ICS combination, meaning one inhaler once a day. Breztri is the other.