Have you heard of or used Nucala?
Yes, Nucala (mepolizumab) is a medication that some people with COPD may have heard about or been prescribed. It's the first biologic approved specifically for adults with COPD who have an eosinophilic phenotype—meaning higher levels of certain inflammation-causing white blood cells called Show Full Answer
Have you heard of or used Nucala?
Yes, Nucala (mepolizumab) is a medication that some people with COPD may have heard about or been prescribed. It's the first biologic approved specifically for adults with COPD who have an eosinophilic phenotype—meaning higher levels of certain inflammation-causing white blood cells called eosinophils.
How does it work?
Nucala is given as a monthly injection and works by targeting a protein called interleukin-5 (IL-5) that's involved in type 2 inflammation. It's designed as an add-on treatment for people who still experience flare-ups despite using inhaled triple therapy.
What does the research show?
Clinical trials found that Nucala significantly reduced moderate and severe COPD flare-ups—including those requiring emergency care or hospitalization—in people with elevated eosinophil counts. Studies suggest that 20 to 40 percent of people with COPD have this type of inflammation.
Is it right for you?
Your doctor would need to test your eosinophil count to determine if Nucala might be appropriate for your situation. It's specifically for those who continue having exacerbations despite being on standard inhaled medications.
Have you discussed eosinophil testing with your doctor, or are you currently exploring add-on treatments beyond inhalers?
February 19
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