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A MyCOPDTeam Member asked a question 💭
Clarkston, WA
April 14
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MyCOPDTeam

Has anyone tried Nucala?

Nucala (mepolizumab) is the first biologic medication approved for adults with COPD who have an eosinophilic phenotype. This means it's specifically for people with COPD who have elevated levels of eosinophils, a type of white blood cell linked to inflammation.

It's used as an add-on treatment for Show Full Answer

Has anyone tried Nucala?

Nucala (mepolizumab) is the first biologic medication approved for adults with COPD who have an eosinophilic phenotype. This means it's specifically for people with COPD who have elevated levels of eosinophils, a type of white blood cell linked to inflammation.

It's used as an add-on treatment for those who still experience flare-ups despite using inhaled triple therapy. Nucala is given as a monthly injection and works by targeting interleukin-5 (IL-5), a protein involved in type 2 inflammation.

In clinical trials, Nucala reduced moderate and severe COPD flare-ups by 21% in people with elevated eosinophil counts. Some of these flare-ups would have required emergency care or hospitalization.

If you're considering Nucala, your doctor would need to test your eosinophil count to see if you're a candidate for this treatment. It's worth discussing with your healthcare provider if you continue to have flare-ups despite your current medications.

Have you had your eosinophil levels checked? Connecting with other members on your Activities page might help you find others who have experience with this medication.

April 14

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