Azithromycin everyday is often prescribed to reduce inflammation and therefore esacerbations in situations where the individual is having exacerbations frequently. Daliresp is another med that is given for the same reason and both are effective. If you don't want to take an antibiotic, suggest daliresp (roflumilast) to your doc. It has been clinically proven to be effective. There is a current study, RELIANCE, that is a head to head comparison to try to determine whether daliresp or azithromycin is more effective and for whom.

I have been on antibiotics for 1.5 years, 1 per day and have not seen much improvement. I have had flare ups while being on them

Why would anyone take antibiotics when they don't have an infection???

I've been on 250mg every day since 2018 and since then only been in hospital once I was constantly getting infection 4 or 5 times a year till I started the daily antibiotic

Yes my partner has copd and has a 250 ml of amoxocillan plus predisonol which he takes as and when he needs them x