Any sent affects you for good or bad

If you're sensitive to scents, paint would probably affect you whether you're on 02 or not.

Just looked closer at your question. I am not on Oxygen.

I painted most of the rooms in our house last summer. Most of the paint (latex) is better than it used to be. Low VOC. I just used the covid masks I had and it was fine. I guess it would depend on the individual tho.