use mine every 4 hours

I would be concerned about taking that much Prednisone. It can have serious side effects. In my case, pressure in eyes -glaucoma. Almost blind in right eye now. Eye specialist told me prednisone was to blame. Crush fracture of vertebtrae in spine. Severe pain. Put me in hospital.

I have a portable made by Aura Medical....carry it in m purse!

It depends on what you're nebulizing. If you have a daily maintenance medication that is in nebulized form, yes, you should use it as prescribed, however many times a day you're supposed to use it.. If you nebulize something like duoneb, you should use it however many times it's prescribed. If you're nebulizing albuterol, which is a rescue medication, you don't have to use it daily; you use it as needed. Many people would use it with albuterol before they exercise or do something strenuous, just like you'd use a rescue inhaler. FYI, PRN does NOT mean every day; it means when you need it. I think your pharmacist was making a good point though: duoneb is an every day med. What you can play with is how many times a day you take it. You can also get the same medication in the Combivent respimat form. It's more expensive, but much quicker than nebulizing. If you can do a good strong inhale, you might think about switching to the Respimat.

Yes, I do, if you are having a hard time breathing, oxygen not helping a lot, use nebulizer !!!!!